{"id":4593,"date":"2024-08-19T14:30:21","date_gmt":"2024-08-19T14:30:21","guid":{"rendered":"https:\/\/medicalaffairs.travere.com\/?post_type=episode&#038;p=4593"},"modified":"2025-09-16T03:03:17","modified_gmt":"2025-09-16T03:03:17","slug":"rethinking-igan-community-nephrologists","status":"publish","type":"episode","link":"https:\/\/clleancode.top\/travere-redesign\/podcasts\/rare-kidney-disease-show\/rethinking-igan-community-nephrologists\/","title":{"rendered":"Rethinking IgAN"},"content":{"rendered":"\r\n\t<section style=\"padding-top:calc(150px * var(--scale));padding-right:0px;padding-bottom:0px;padding-left:0px;\" class=\"section-container has-background-image wp-elements-8f30fe365fd7ac49b759d7d5b44f4a21 wp-block-grizzly-section-container has-text-color has-white-color has-background has-blue-background-color\">\r\n\t\t<img loading=\"lazy\" decoding=\"async\" width=\"1920\" height=\"897\" src=\"https:\/\/clleancode.top\/travere-redesign\/wp-content\/uploads\/2024\/03\/Header.png\" class=\"hero-section-layer\" alt=\"\" srcset=\"https:\/\/clleancode.top\/travere-redesign\/wp-content\/uploads\/2024\/03\/Header.png 1920w, https:\/\/clleancode.top\/travere-redesign\/wp-content\/uploads\/2024\/03\/Header-300x140.webp 300w, https:\/\/clleancode.top\/travere-redesign\/wp-content\/uploads\/2024\/03\/Header-1024x478.webp 1024w, https:\/\/clleancode.top\/travere-redesign\/wp-content\/uploads\/2024\/03\/Header-768x359.webp 768w, https:\/\/clleancode.top\/travere-redesign\/wp-content\/uploads\/2024\/03\/Header-1536x718.webp 1536w, https:\/\/clleancode.top\/travere-redesign\/wp-content\/uploads\/2024\/03\/Header-290x135.webp 290w\" sizes=\"auto, (max-width: 1920px) 100vw, 1920px\" \/>\t\t<div class=\"container\">\r\n\t\t\t\n\n<h1 class=\"wp-block-heading has-text-align-center\" id=\"h-rethinking-igan-a-different-perspective-from-community-nephrologists\" style=\"margin-bottom:calc(45px * var(--scale))\">Rethinking IgAN: A Different Perspective From Community Nephrologists<\/h1>\n\n\n<div class=\"podcast\">\n\t\t\t\t<iframe src=\"https:\/\/share.transistor.fm\/e\/f1ed7451?color=06304B&#038;background=ffffff\" title=\"Podcast Player\" frameborder=\"0\" allowfullscreen loading=\"lazy\"><\/iframe>\n\t<\/div>\n\t\t<\/div>\r\n\t<\/section>\r\n\t\t\t<svg width=\"100%\" viewBox=\"0 0 1440 95\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"wave\">\r\n\t\t\t<path d=\"M0 94.883h1440v-55C971.349 142.422 479-88.172 0 39.828v55.055Z\" fill=\"#fff\"\/>\r\n\t\t<\/svg>\r\n\t\n\n\r\n\t<section style=\"padding-top:calc(30px * var(--scale));padding-right:0px;padding-bottom:calc(30px * var(--scale));padding-left:0px;\" class=\"section-container wp-block-grizzly-section-container\">\r\n\t\t\t\t<div class=\"container\">\r\n\t\t\t\n\n<div class=\"wp-block-group is-layout-constrained wp-container-core-group-is-layout-09ab29e6 wp-block-group-is-layout-constrained\" style=\"margin-bottom:calc(45px * var(--scale))\">\n<p class=\"has-text-align-center\" style=\"margin-bottom:calc(60px * var(--scale))\">Luis E. Velez, MD is a board-certified community nephrologist in San Antonio, TX, with expertise in hypertension and glomerular disorders.<\/p>\n\n\n\n<p class=\"has-text-align-center\" style=\"margin-bottom:calc(60px * var(--scale))\">Jessica Coleman, MD is a board-certified community nephrologist practicing between Savannah, GA, and Charleston, SC, with expertise in hypertension and glomerular disorders.<\/p>\n\n\n\n<p class=\"has-text-align-center\">In this episode, Dr. Velez and Dr. Coleman discuss management of patients with IgA nephropathy from a community nephrologist perspective. They discuss how their management of IgA nephropathy has evolved, highlighting that new data, like the <a href=\"https:\/\/clleancode.top\/travere-redesign\/publications\/long-term-outcomes-in-iga-nephropathy\/\">RaDaR study<\/a>, have been key drivers of change. With greater awareness of the role of proteinuria in IgA nephropathy, they advocate for early and aggressive treatment to avoid long-term complications.<\/p>\n<\/div>\n\n\n<div class=\"platforms\">\n\t\t\t\t<p>Also find us on:\n\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/podcasts.apple.com\/us\/podcast\/rethinking-igan-a-different-perspective-from\/id1741835387?i=1000665622654\" target=\"_blank\" rel=\"noreferrer noopener\" class=\"platform-links--border\">\n\t\t\t\t\t\t<span class=\"icon2-apple-podcast\" aria-hidden=\"true\"><\/span> Apple Podcasts\n\t\t\t\t\t<\/a>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/open.spotify.com\/episode\/4BK2Q6eHAgUQWI2WdY48Gd?si=5874a59cf3414cff\" target=\"_blank\" rel=\"noreferrer noopener\" class=\"platform-links--border\">\n\t\t\t\t\t\t<span class=\"icon2-spotify\" aria-hidden=\"true\"><\/span> Spotify\n\t\t\t\t\t<\/a>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t<\/p>\n\t<\/div>\n\t\t<\/div>\r\n\t<\/section>\r\n\t\n\n\r\n\t<section style=\"padding-top:calc(60px * var(--scale));padding-right:0px;padding-bottom:calc(60px * var(--scale));padding-left:0px; background-color:#f8f8f8;\" class=\"section-container wp-block-grizzly-section-container has-background\">\r\n\t\t\t\t<div class=\"container\">\r\n\t\t\t\n\n<div class=\"wp-block-group is-layout-constrained wp-container-core-group-is-layout-09ab29e6 wp-block-group-is-layout-constrained\">\n<h2 class=\"wp-block-heading has-heading-3-font-size has-text-color has-link-color wp-elements-e4f52c3ea4e9e98cf562e94e619e7d49\" id=\"h-episode-summary\" style=\"color:#00b49e;margin-bottom:calc(60px * var(--scale))\"><strong>Episode Summary<\/strong><\/h2>\n\n\n\t\t<div class=\"summary-block\">\n\t\t\t<p>&#8220;RaDaR taught me that the traditional way of looking at IgA nephropathy is wrong. We realized this is a disease state that absolutely can progress and can progress more rapidly than what we initially appreciated and certainly at a younger age in these patients.&#8221; (02:25)<\/p> \n\t\t<\/div>\n\n\n\t\t<div class=\"summary-block\">\n\t\t\t<p>&#8220;When we look at patients with proteinuria, even just 0.5 g\/d, a third of patients under 40 are going to progress to end-stage kidney disease in ten years [RaDaR].&#8221; (04:30)<\/p> \n\t\t<\/div>\n\n\n\t\t<div class=\"summary-block\">\n\t\t\t<p>\u201cWith the RaDaR data, we see levels of proteinuria 0.5-0.8 g\/d still being significant markers for disease progression.&#8221; (08:56)<\/p> \n\t\t<\/div>\n\n\n<div class=\"wp-block-list-wrapper\">\n<ul class=\"wp-block-list\">\n<li>IgA nephropathy is not a benign disease.<\/li>\n\n\n\n<li>Proteinuria is the most important prognostic indicator of disease progression in IgA nephropathy. <\/li>\n\n\n\n<li>Recent data support targeting a lower proteinuria goal to achieve complete remission (&lt;0.3 g\/d).<\/li>\n<\/ul>\n<\/div>\n\n\n<div style=\"height:38px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p><strong>Disclaimer:<\/strong> Guest speakers of the Rare Kidney Disease Show may be paid consultants of Travere Therapeutics. This podcast episode was recorded on August 16, 2024. Please always consult updated sources for the latest information, as information discussed may have changed since the recording date.<\/p>\n\n\n\n<p class=\"smaller-text\" style=\"margin-top:calc(60px * var(--scale))\">MA-SP-24-0094<\/p>\n<\/div>\n\n\t\t<\/div>\r\n\t<\/section>\r\n\t\n\n\r\n\t<section class=\"section-container wp-block-grizzly-section-container\">\r\n\t\t\t\t<div class=\"container\">\r\n\t\t\t\n\n<div class=\"wp-block-group is-layout-constrained wp-container-core-group-is-layout-09ab29e6 wp-block-group-is-layout-constrained\" style=\"margin-bottom:calc(45px * var(--scale));padding-top:calc(60px * var(--scale));padding-bottom:calc(60px * var(--scale))\">\n<div id=\"episodes\" class=\"episodes\" style=\"\">\n\t<div class=\"episodes-title\">\n\t\t<p class=\"has-heading-3-font-size\">Episodes<\/p>\n\t\t\t<\/div>\n\n\t\t\t\t<div class=\"episodes-list\">\n\t\t\t\t\t<article class=\"m-card m-card--podcast \">\n\t\t<div class=\"m-card__top\">\n\t\t\t<a href=\"https:\/\/clleancode.top\/travere-redesign\/podcasts\/rare-kidney-disease-show\/spartan-biomarkers\/\"  aria-label=\"View episode: Insights from the SPARTAN Study\">\n\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"2560\" height=\"2560\" src=\"https:\/\/clleancode.top\/travere-redesign\/wp-content\/uploads\/2025\/09\/RKD-Show-SPARTAN-Artwork-scaled.webp\" class=\"a-img h-object-position-top-center\" alt=\"Insights from the SPARTAN Study\" loading=\"lazy\" srcset=\"https:\/\/clleancode.top\/travere-redesign\/wp-content\/uploads\/2025\/09\/RKD-Show-SPARTAN-Artwork-scaled.webp 2560w, https:\/\/clleancode.top\/travere-redesign\/wp-content\/uploads\/2025\/09\/RKD-Show-SPARTAN-Artwork-300x300.webp 300w, https:\/\/clleancode.top\/travere-redesign\/wp-content\/uploads\/2025\/09\/RKD-Show-SPARTAN-Artwork-1024x1024.webp 1024w, https:\/\/clleancode.top\/travere-redesign\/wp-content\/uploads\/2025\/09\/RKD-Show-SPARTAN-Artwork-150x150.webp 150w, https:\/\/clleancode.top\/travere-redesign\/wp-content\/uploads\/2025\/09\/RKD-Show-SPARTAN-Artwork-768x768.webp 768w, https:\/\/clleancode.top\/travere-redesign\/wp-content\/uploads\/2025\/09\/RKD-Show-SPARTAN-Artwork-1536x1536.webp 1536w, https:\/\/clleancode.top\/travere-redesign\/wp-content\/uploads\/2025\/09\/RKD-Show-SPARTAN-Artwork-2048x2048.webp 2048w, https:\/\/clleancode.top\/travere-redesign\/wp-content\/uploads\/2025\/09\/RKD-Show-SPARTAN-Artwork-290x290.webp 290w\" sizes=\"auto, (max-width: 2560px) 100vw, 2560px\" \/>\t\t\t\t\t\t\t<\/a>\n\t\t\t<div class=\"m-card__info\">\n\t\t\t\t<div class=\"m-tags\">\n\t\t\t\t\t<span class=\"a-tag h-blue\">\n\t\t\t\t\t\t<i class=\"icon2-apple-podcast\"><\/i> Podcast\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<span class=\"a-tag h-blue\">Nephrology<\/span><span class=\"a-tag h-blue\">IgAN<\/span>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t<div class=\"m-card__bottom m-card--padding\">\n\t\t\t<div class=\"m-card__text\">\n\t\t\t\t<p class=\"a-heading a-heading--h4 h-ultra-dark-blue h-text-ellipsis h-w-medium\">\n\t\t\t\t\tInsights from the SPARTAN Study\t\t\t\t<\/p>\n\t\t\t\t\t\t\t\t<p class=\"a-text a-text--m h-ultra-dark-blue\">Ft. Drs. Jonathan Barratt and Shikha Wadhwani<\/p>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<a href=\"https:\/\/clleancode.top\/travere-redesign\/podcasts\/rare-kidney-disease-show\/spartan-biomarkers\/\" class=\"a-btn a-btn--secondary--blue\"  aria-label=\"Listen to episode: Insights from the SPARTAN Study\">\n\t\t\t\t\t\t<span>Listen to episode<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t\t<\/div>\n\t<\/article>\n\t<article class=\"m-card m-card--podcast \">\n\t\t<div class=\"m-card__top\">\n\t\t\t<a href=\"https:\/\/clleancode.top\/travere-redesign\/podcasts\/rare-kidney-disease-show\/fsgs-podocytopathy\/\"  aria-label=\"View episode: From Podocyte to Patient\">\n\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"2560\" height=\"2560\" src=\"https:\/\/clleancode.top\/travere-redesign\/wp-content\/uploads\/2025\/06\/Ep-7-graphic-scaled.webp\" class=\"a-img h-object-position-top-center\" alt=\"From Podocyte to Patient\" loading=\"lazy\" srcset=\"https:\/\/clleancode.top\/travere-redesign\/wp-content\/uploads\/2025\/06\/Ep-7-graphic-scaled.webp 2560w, https:\/\/clleancode.top\/travere-redesign\/wp-content\/uploads\/2025\/06\/Ep-7-graphic-300x300.webp 300w, https:\/\/clleancode.top\/travere-redesign\/wp-content\/uploads\/2025\/06\/Ep-7-graphic-1024x1024.webp 1024w, https:\/\/clleancode.top\/travere-redesign\/wp-content\/uploads\/2025\/06\/Ep-7-graphic-150x150.webp 150w, https:\/\/clleancode.top\/travere-redesign\/wp-content\/uploads\/2025\/06\/Ep-7-graphic-768x768.webp 768w, https:\/\/clleancode.top\/travere-redesign\/wp-content\/uploads\/2025\/06\/Ep-7-graphic-1536x1536.webp 1536w, https:\/\/clleancode.top\/travere-redesign\/wp-content\/uploads\/2025\/06\/Ep-7-graphic-2048x2048.webp 2048w, https:\/\/clleancode.top\/travere-redesign\/wp-content\/uploads\/2025\/06\/Ep-7-graphic-290x290.webp 290w\" sizes=\"auto, (max-width: 2560px) 100vw, 2560px\" \/>\t\t\t\t\t\t\t<\/a>\n\t\t\t<div class=\"m-card__info\">\n\t\t\t\t<div class=\"m-tags\">\n\t\t\t\t\t<span class=\"a-tag h-blue\">\n\t\t\t\t\t\t<i class=\"icon2-apple-podcast\"><\/i> Podcast\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<span class=\"a-tag h-blue\">Nephrology<\/span><span class=\"a-tag h-blue\">FSGS<\/span>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t<div class=\"m-card__bottom m-card--padding\">\n\t\t\t<div class=\"m-card__text\">\n\t\t\t\t<p class=\"a-heading a-heading--h4 h-ultra-dark-blue h-text-ellipsis h-w-medium\">\n\t\t\t\t\tFrom Podocyte to Patient\t\t\t\t<\/p>\n\t\t\t\t\t\t\t\t<p class=\"a-text a-text--m h-ultra-dark-blue\">The Pathophysiology of FSGS<\/p>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<a href=\"https:\/\/clleancode.top\/travere-redesign\/podcasts\/rare-kidney-disease-show\/fsgs-podocytopathy\/\" class=\"a-btn a-btn--secondary--blue\"  aria-label=\"Listen to episode: From Podocyte to Patient\">\n\t\t\t\t\t\t<span>Listen to episode<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t\t<\/div>\n\t<\/article>\n\t<article class=\"m-card m-card--podcast \">\n\t\t<div class=\"m-card__top\">\n\t\t\t<a href=\"https:\/\/clleancode.top\/travere-redesign\/podcasts\/rare-kidney-disease-show\/fsgs-introduction\/\"  aria-label=\"View episode: Introduction to FSGS\">\n\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"2560\" height=\"2560\" src=\"https:\/\/clleancode.top\/travere-redesign\/wp-content\/uploads\/2025\/01\/Ep-6-graphic-scaled.webp\" class=\"a-img h-object-position-top-center\" alt=\"Introduction to FSGS\" loading=\"lazy\" srcset=\"https:\/\/clleancode.top\/travere-redesign\/wp-content\/uploads\/2025\/01\/Ep-6-graphic-scaled.webp 2560w, https:\/\/clleancode.top\/travere-redesign\/wp-content\/uploads\/2025\/01\/Ep-6-graphic-300x300.webp 300w, https:\/\/clleancode.top\/travere-redesign\/wp-content\/uploads\/2025\/01\/Ep-6-graphic-1024x1024.webp 1024w, https:\/\/clleancode.top\/travere-redesign\/wp-content\/uploads\/2025\/01\/Ep-6-graphic-150x150.webp 150w, https:\/\/clleancode.top\/travere-redesign\/wp-content\/uploads\/2025\/01\/Ep-6-graphic-768x768.webp 768w, https:\/\/clleancode.top\/travere-redesign\/wp-content\/uploads\/2025\/01\/Ep-6-graphic-1536x1536.webp 1536w, https:\/\/clleancode.top\/travere-redesign\/wp-content\/uploads\/2025\/01\/Ep-6-graphic-2048x2048.webp 2048w, https:\/\/clleancode.top\/travere-redesign\/wp-content\/uploads\/2025\/01\/Ep-6-graphic-290x290.webp 290w\" sizes=\"auto, (max-width: 2560px) 100vw, 2560px\" \/>\t\t\t\t\t\t\t<\/a>\n\t\t\t<div class=\"m-card__info\">\n\t\t\t\t<div class=\"m-tags\">\n\t\t\t\t\t<span class=\"a-tag h-blue\">\n\t\t\t\t\t\t<i class=\"icon2-apple-podcast\"><\/i> Podcast\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<span class=\"a-tag h-blue\">Nephrology<\/span><span class=\"a-tag h-blue\">FSGS<\/span>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t<div class=\"m-card__bottom m-card--padding\">\n\t\t\t<div class=\"m-card__text\">\n\t\t\t\t<p class=\"a-heading a-heading--h4 h-ultra-dark-blue h-text-ellipsis h-w-medium\">\n\t\t\t\t\tIntroduction to FSGS\t\t\t\t<\/p>\n\t\t\t\t\t\t\t\t<p class=\"a-text a-text--m h-ultra-dark-blue\">Ft. Dr. Howard Trachtman<\/p>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<a href=\"https:\/\/clleancode.top\/travere-redesign\/podcasts\/rare-kidney-disease-show\/fsgs-introduction\/\" class=\"a-btn a-btn--secondary--blue\"  aria-label=\"Listen to episode: Introduction to FSGS\">\n\t\t\t\t\t\t<span>Listen to episode<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t\t<\/div>\n\t<\/article>\n\t\t\t<\/div>\n\t\t\t\t<\/div>\n\n\n<p class=\"has-text-align-right smaller-text\" style=\"margin-top:calc(60px * var(--scale));margin-bottom:calc(180px * var(--scale))\">MA-DS-24-0029 | August 2025<\/p>\n<\/div>\n\n\t\t<\/div>\r\n\t<\/section>\r\n\t","protected":false},"featured_media":6172,"parent":5968,"menu_order":0,"template":"","meta":{"inline_featured_image":false,"header_bg_color":"transparent","header_fixed":true,"post_description":"","post_download_link":""},"product":[142],"therapeutic_area":[97],"disease_area":[174],"study_registry":[184],"study_type":[182],"resource_type":[196],"class_list":["post-4593","episode","type-episode","status-publish","has-post-thumbnail","hentry","product-non-product-disease-state","therapeutic_area-neph","disease_area-igan","study_registry-radar","study_type-observational","resource_type-podcast"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v24.9 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Rethinking IgAN in Community Nephrology | RKD Show | Travere Medical Affairs<\/title>\n<meta name=\"description\" content=\"In this episode, community nephrologists Dr. Velez and Dr. Coleman discuss management of patients with IgAN. 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